Table 3.

Multivariable analysis of prognostic factors for DFS.

Variable	Univariate Analysis			Multivariate Analysis
	HR	95% CI	p-Value	HR	95% CI	p-Value
Age
<63 vs. ≥63	0.72	0.38–1.36	0.288
Chronic disease
Yes vs. No	0.63	0.30–1.31	0.215
Hysterectomy
Yes vs. No	1.02	0.55–1.89	0.947
Tumor-stage
T1/T2 vs. T3/T4	2.27	1.23–4.16	0.008 *	1.65	0.86–3.15	0.134
Tumor diameter at diagnosis
≤4 cm vs. >4 cm	1.92	1.03–3.57	0.041 *	1.42	0.73–2.73	0.301
Lymph node metastases
Yes vs. No	2.75	1.50–5.03	0.001 *	2.24	1.18–4.22	0.013 *
Concomitant chemotherapy
Yes vs. No	1.72	0.38–1.36	0.311
CTV volume at brachytherapy
<17.6 cm3 vs. ≥17.6 cm3	1.10	0.55–2.18	0.794

* Statistically significant; HR = hazard ratio; CI = confidence interval; vs. = versus; CTV = clinical target volume.