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. 2021 Mar 23;13(6):1480. doi: 10.3390/cancers13061480

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Validation of differentially expressed miRNAs in different PSCC histological subtypes as determined by TaqMan^® RT-qPCR (p ≤ 0.05). (a) Mean ΔCt values of (HPV-negative) usual PSCC and normal tissue samples; (b,c) mean ΔCt values of metastatic versus non-metastatic usual (HPV-negative) tumors; (d) mean ΔCt values of warty–basaloid (HPV-positive) PSCC versus normal tissue samples. Lower ΔCt implies higher expression level. Mann–Whitney U test was used to determine p-values, FC: Fold change.