Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Quality by design approach.
| Critical Quality Attribute (CQA) | Units Measured | Desired Range |
|---|---|---|
| Encapsulation Efficiency (EE%) | % total siRNA | >50% |
| Zeta Potential (ζ) | millivolts (mV) | <10 mV |
| Average Size | diameter (nm) | <100 nm |
| Polydispersity Index (PDI) | N/A | <0.2 |
