Table 3.
Screening of commercially available amines with structures similar to 3 and 13 (The biological activities are based on the molecular weight of the proposed structures).
| Name and CAS no. | Structures | MRSA | E. coli | P. aeruginosa | M. tuberculosis | HepG2 | HEK 293 | A549 | THP-1 |
|---|---|---|---|---|---|---|---|---|---|
|
Hexylamine 111-26-2 |
|
>100 | >100 | 50 | >100 | >100 | >100 | >100 | >100 |
|
Dihexylamine 143-16-8 |
|
12.5 | 12.5 | 6.2 | >100 | >100 | >100 | >100 | >100 |
|
Dioctylamine 1120-48-5 |
|
6.2 | 6.2 | 3 | >100 | >100 | >100 | >100 | >100 |
|
Triethylamine 121-44-8 |
|
>100 | >100 | >100 | >100 | >100 | >100 | >100 | >100 |
|
Tributylamine 102-82-9 |
|
>100 | >100 | 50 | >100 | >100 | >100 | >100 | >100 |
|
Trihexylamine 102-86-3 |
|
3 | 3 | 6.5 | >100 | >100 | 50 | >100 | >100 |
|
Trioctylamine 1116-76-3 |
|
12.5 | 25 | 25 | 0.02 | >100 | 6 | 50 | 3.1 |