Table 6.
Screening of compounds with structures inspired by ascididemin which include three aromatic rings.
| Name and CAS no. | Structures | MRSA | E. coli | P. aeruginosa | TB. H37Rv | HepG2 | HEK 293 | A549 | THP-1 |
|---|---|---|---|---|---|---|---|---|---|
| 4,7-Dimethyl-1,10-Phenanthrolin 3248-05-3 |
|
0.3 | 0.3 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
| Neocuproine hemihydrate 34302-69-7 |
|
0.09 | 0.3 | 0.04 | 0.1 | 0.1 | 0.1 | 6.2 | 12 |
| 5,6-Dimethyl-1,10-phenanthroline 3002-81-1 |
|
0.3 | 0.78 | >100 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
| 3,4,7,8-Tetramethyl-1,10-phenanthroline 1660-93-1 |
|
0.3 | 0.3 | 0.3 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
| 1,10-Phenanthroline-5,6-dione 27318-90-7 |
|
0.04 | 0.04 | 0.04 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |