Table 7.
Screening of compounds with structures inspired by ascididemin which include three aromatic rings plus further modifications.
| Name and CAS no. | Structures | MRSA | E. coli | P. aeruginosa | TB. H37Rv | HepG2 | HEK 293 | A549 | THP-1 |
|---|---|---|---|---|---|---|---|---|---|
| 5-Nitro-1,10-phenanthroline 4199-88-6 |
|
0.09 | 0.78 | >100 | 0.1 | 0.1 | 0.1 | 12 | 0.1 |
| Bathophenanthroline 1662-01-7 |
|
0.09 | 0.019 | 0.03 | 0.01 | 1.5 | 25 | 3 | 13 |
| 2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline 4733-39-5 |
|
25 | 0.78 | 50 | 50 | 0.1 | 0.1 | >100 | >100 |
| Bathocuproinedisulfonic acid sodium salt 1257642-74-2 |
|
>100 | >100 | 0.19 | 1.2 | 50 | 0.1 | >100 | >100 |