Figure 8.

Predicted phase diagrams of (a) SA/NA, (b) CBZ/NA, and (c) TP/CA showing the thermodynamically stable phases depending on the mass fraction of the dry, xylitol-free system and RH for the presence of xylitol next to the CC at 298.15 K. Thin solid lines indicate phase boundaries. Vertical dash-dotted lines mark CC stoichiometries. Above the solid horizontal lines (shaded region L), deliquescence is predicted to occur in case that xylitol is present, whereas as above the dotted lines, deliquescence is predicted to occur in the xylitol-free system. Symbols indicate results of CC/xylitol stability measurements after 49 days of storage. Triangles represent unchanged samples. White circles indicate the occurrence of deliquescence during storage.