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. 2021 Mar 23;13(3):433. doi: 10.3390/pharmaceutics13030433

Table 3.

Properties used to calculate the hydrate solubility product and the resulting hydrate solubility product at 298.15 K.

Hydrate Stoichiometry Transition Polymorph Ttrans/K Δhtrans/kJ mol1 Ks,hydrate * at 298.15 K References
CA/water 1:1 anhydrate 309.45 10.85 0.0152 [16,44,45]
CBZ/water 1:2 III 343.15 15.06 0.0256 [19,46]
TP/water 1:1 II 340 13.81 0.0634 [19,47]

* Ks,hydrate is without unit since it is based on thermodynamic activities.