Table 2.

The experimental arrangement and results of Box-Behnken design.

Number	Amount of Solid Carrier (X1)	Feed Pump Parameter (X2)	Inlet Air Temperature (X3)/°C	Oil Leakage Rate (Y1)/%	Droplet Size of Reconstituted Emulsion (Y2)/μm	Drug Content in Solid NSSPE (Y3)/mgg−1
1	0(10%)	0 (15)	0(130)	0	4.08	38.95
2	0(10%)	0(15)	0(130)	0	3.65	38.68
3	0(10%)	0(15)	0(130)	0	3.57	38.65
4	0(10%)	0(15)	0(130)	0	4.00	38.79
5	0(10%)	0(15)	0(130)	0	4.49	38.86
6	0(10%)	1(25)	−1(110)	0	4.04	38.56
7	−1(5%)	0(15)	1(150)	1.52	8.04	53.05
8	0(10%)	1(25)	1(150)	0	3.55	37.78
9	0(10%)	−1(5)	1(150)	0	3.61	39.08
10	−1(5%)	1(25)	0(130)	1.39	7.16	60.07
11	1(15%)	0(15)	−1(110)	0	3.00	29.56
12	1(15%)	1(25)	0(130)	0	2.62	29.90
13	−1(5%)	−1(5)	0(130)	1.69	7.31	57.53
14	1(15%)	0(15)	1(150)	0	2.78	31.59
15	1(15%)	−1(5)	0(130)	0	3.10	30.53
16	0(10%)	−1(5)	−1(110)	0	4.28	37.87
17	−1(5%)	0(15)	−1(110)	1.36	8.18	56.48