Table 2.
Applications of LC to characterize bioactive compound from natural sources.
| LC Platform |
MS Detector |
Column | Ionization Mode | Compounds Detected | Matrix | Ref. |
|---|---|---|---|---|---|---|
| HPLC | TOF | Zorbax Eclipse Plus C18 | Negative | Organic acids, phenolic acids and flavonoids | Hibiscus sabdariffa | [51] |
| RP18 | Negative | Flavonoids, terpenoids | Rosemary officinalis | [52] | ||
| Zorbax Eclipse Plus C18 | Negative | Iridoid glycosides, flavonoids and phenylethanoids | Lippia ciriodora | [53] | ||
| Quadrupole | Eclipse XDB C18 | Positive | Anthocyanins | Allium cepa | [54] | |
| Phenomenex Luna C18 | Negative | Phenolic acids and flavonoids | Curcuma longa | [55] | ||
| Triple Quad | Zorbax Eclipse XDB-C18 | Negative | Phenolic compounds | Trametes versicolor | [56] | |
| Q-TOF | YMC C30 Synergi Hydro-RPC18 |
Positive and negative | Carotenoids, organic acids, phenolic acids and flavonoids | Hibiscus sabdariffa | [57] | |
| Zorbax Eclipse Plus C18 | Negative | Flavonoids | Theobroma cacao | [58] | ||
| Orbitrap | Zorbax Eclipse XDB-C18 | Positive and negative | Flavonoids | Allium ampeloprasum | [59] | |
| Zorbax Eclipse Plus C18 | Negative | Secoiridoids, flavonoids and related compounds | Olea europaea | [60] | ||
| Qtrap | Waters Spherisorb S3 ODS-2 C18 |
Negative | Phenolic acids and flavonoids | Rosemary officinalis | [61] | |
| UHPLC | TOF | Acquity UHPLC BEH C18 | Positive and negative | phenolic acids flavonoids and gallotanins | Camellia sinensis | [62] |
| Quadrupole | Acquity UHPLC BEH C18 | Positive | Valifenalate | Vitis vinifera | [63] | |
| Acquity HSS T3 | Positive and negative | Hydroxycinnamic acids | Vitis vinifera | [64] | ||
| Acquity UPLC shield RP-18 | Negative | Epigallocatechin | Camellia sinensis | [65] | ||
| Q-TOF | Waters ACQUITY UPLC BEH C18 | Negative | Phenolic acids, flavonoids | Glechoma longituba | [66] | |
| Waters HSS-T3 column Waters C18 BEH Waters BEH-Amide |
Positive and negative | Phenolic acids, anthocyanins and organosulfur compounds | Allium sativum | [67] | ||
| ACQUITY UPLC HSS T3 | Negative | Procyanidin | Theobroma cacao | [68] | ||
| Hypersil Gold | Negative | Terpenes, flavonoids, phenolic acids | Rosemary officinalis | [69] | ||
| Waters Acquity UPLC C8 | Positive and negative | Epigallocatechin gallates | Camellia sinensis | [70] | ||
| Orbitrap | Phenomenex Luna C18 | Positive and negative | Phenolic acids, flavonoids, tannins and anthocyanin-derived pigments | Punica granatum | [71] | |
| Zorbax SB-C18 | Negative | Stilbenes | Vitis Vinifera | [72] |