Table 2.

Some synthetic polymers frequently used for nucleic acids (NA) delivery.

Abbreviation	Chemical Name	Findings/Relevant Properties	Reference
PEI	Polyethylenimine	The most widely used. It is the organic macromolecule with the highest cationic-charge-density potential.	[90,111]
pDMAEMA	Poly(2-dimethylamino)ethyl methacrylate	Extensively studied and widely used for the delivery of DNA, siRNA, mRNA and miRNA. It had tertiary amines in its structure.	[126]
hDD90-118	-	An hyperbranched poly(beta amino ester) capable of save and effective delivering of mRNA to lung epithelium.	[127]
N5	-	An assembly of poly A binding proteins and cationic polypeptides for enhanced mRNA delivery.	[128]
PAA8k-(2-3-2)	-	A poly(acrylic acid) scaffold grafted with oligoalkylamines promoting enhanced mRNA delivery.	[129]