Table 1.

The summary of ACE inhibitory peptides by conventional approach and affinity purification on different medium.

Sources	Amino Sequence	IC50	Method of Purification	Reference
lizard fish	RVCLP	175 µM	Conventional approach	[29]
	RYRP	52 µM	Affinity purification/ IMAC-Ni2+	[39]
	GMKCAF	45.7 ± 1.1 µM	Affinity purification/ Magnetic agarose-ACE	[6]
casein	MKP	0.3 μM	Conventional approach	[40]
	WYLHYA	16.2 μM	Affinity purification/ IMAC-Ni2+	[41]
	LLYQEPVLGPVR	274 ± 5 μM	Affinity purification/ IMAM @ mPEG	[9]
Pinctada fucata martensii	HLHT/GWA	458.06 ± 3.24 μM/ 109.25 ± 1.45 μM	Affinity purification/ IMAM @ mPEG	[10]
Volutharpa ampullaceal perryi	IVTNWDDMGK/ VGPAGRRG	2.08 mM/4.66 mM	Affinity purification/ Zn-SBA-15-ACE	[12]
Wakame	AIYK/YKYY/ KFYG/YNKL	213 μM/64.2 μM/ 90.5 μM/21 μM/	Conventional approach	[28]
	KNFL	225.87 ± 2.70 µM	Affinity purification/ Fe3O4@ZIF-90-ACE	This study