Table 4.
Clinical performance of different assay combinations in probable IA and possible IFD cases if both/all biomarkers had to be positive. PPV and NPV, positive and negative predictive value, respectively; OR, odds ratio; CI, confidential interval.
| % (95% CI) | ||||
|---|---|---|---|---|
| BDG/PCR | BDG/GM | GM/PCR | BDG/GM/PCR | |
| Sensitivity | 60 (17–95) | 40 (5–85) | 40 (5–85) | 40 (5–85) |
| Specificity | 100 (83–100) | 95 (75–100) | 100 (83–100) | 100 (83–100) |
| PPV | 100 (29–100) | 67 (9–99) | 100 (16–100) | 100 (16–100) |
| NPV | 91 (71–99) | 86 (65–97) | 87 (66–97) | 87 (66–97) |
| OR | 57 (2–1468) | 13 (1–187) | 29 (1–749) | 29 (1–749) |