Table 1.
Baseline characteristics of all invasive melanoma subtypes (National Cancer Database; NCDB 2004–2015).
| Invasive Melanoma (All Cases) | Cutaneous Melanoma n = 393,750 (%) |
Ocular Melanoma n = 17,713 (%) |
Mucosal Melanoma n = 7435 (%) |
Chi-Squared p-Value |
|---|---|---|---|---|
| Females | 166,288 (42.23) | 8491 (47.94) | 5237 (70.44) | <0.001 |
| Age | <0.001 | |||
| ≤30 Years | 17,498 (4.44) | 423 (2.39) | 126 (1.69) | |
| 31 to 64 Years | 202,128 (51.33) | 9153 (51.67) | 2697 (36.27) | |
| ≥65 Years | 174,124 (44.22) | 8137 (45.94) | 4612 (62.03) | |
| Race | <0.001 | |||
| Caucasian | 383,462 (97.39) | 16,861 (95.19) | 6681 (89.86) | |
| African American | 2382 (0.60) | 178 (1.00) | 380 (5.11) | |
| Charlson Deyo score | <0.001 | |||
| 0 | 338,934 (86.08) | 14,698 (82.98) | 5959 (80.15) | |
| 1 | 43,252 (10.98) | 2428 (13.71) | 1132 (15.23) | |
| 2 | 8529 (2.17) | 426 (2.41) | 249 (3.35) | |
| ≥3 | 3035 (0.77) | 161 (0.91) | 95 (1.28) | |
| Positive Lymph Nodes identified | 45,177 (11.64) | 18 (0.11) | 1211 (16.76) | <0.001 |
| Metastatic disease at diagnosis | 19,492 (5.11) | 326 (1.90) | 873 (12.61) | <0.001 |
| Died | 103,211 (26.21) | 5388 (30.98) | 4947 (66.54) | <0.001 |
| Insurance Status | <0.001 | |||
| Not insured | 9674 (2.46) | 600 (3.39) | 187 (2.52) | |
| Private insurance | 206,840 (52.53) | 8486 (47.91) | 2608 (35.08) | |
| Medicaid | 10,145 (2.58) | 534 (3.01) | 274 (3.69) | |
| Medicare or other government insurance | 167,091(42.44) | 8093 (45.69) | 4366 (58.72) | |
| Education Level: Number of adults in the patient’s zip code who did not graduate from high school | <0.001 | |||
| >29% (level 1) | 27,642 (7.05) | 1739 (9.86) | 792 (10.70) | |
| 20–28.9% (level 2) | 69,139 (17.63) | 3712 (21.06) | 1557 (21.04) | |
| 14–18.9% (level 3) | 100,822 (25.71) | 4836 (27.43) | 1958 (26.46) | |
| <14% (level 4) | 194,588 (49.62) | 7342 (41.65) | 3098 (41.80) | |
| Socioeconomic Status: Median household income for patient’s zip code | <0.001 | |||
| <40,227 (level 1) | 22,270 (5.68) | 1401 (7.95) | 633 (8.56) | |
| 40,227–50,353 (level 2) | 55,505 (14.16) | 3226 (18.30) | 1224 (16.54) | |
| 50,354–63,332 (level 3) | 104,836 (26.74) | 5190 (29.45) | 2066 (27.92) | |
| >46,000 to >63,333 (level 4) | 209,444 (53.42) | 7808 (44.30) | 3476 (46.98) | |
| Treating Facility Type | <0.001 | |||
| Community cancer program | 145,618 (41.61) | 2361 (14.27) | 2586 (36.14) | |
| Academic/research program | 162,245 (46.36) | 12,823 (77.49) | 3716 (51.94) | |
| Integrated Network Cancer Program | 42,114 (12.03) | 1365 (8.25) | 853 (11.92) | |
| Received Radiation therapy | 16,473 (4.21) | 12,256 (69.33) | 2350 (31.86) | <0.001 |
| Underwent Surgery | 368,260 (93.58) | 5852 (33.08) | 6217 (83.72) | <0.001 |
| Received Systemic therapy | 29,415 (7.53) | 612 (3.47) | 1628 (22.17) | <0.001 |