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. 2021 Mar 23;10(3):713. doi: 10.3390/cells10030713

Table 9.

Advantages and disadvantages of SD-TEVGs in different material.

SD-TEVG Type Advantages Disadvantages
Synthetic SD-TEVGs

  • Easy availability and customization.

  • Biological incompatibility and thrombogenicity.
Natural SD-TEVGs

  • Low immunogenicity and high biological compatibility (allogeneic).

  • Adequate mechanical strength (native ECM-based).

  • Immunogenicity and thrombogenicity (xenogeneic)

  • Weakness in mechanical strength (natural polymer-based).

  • Limited availability (native ECM-based).
Hybrid SD-TEVGs

  • Biological compatibility

  • Adequate mechanical strength

  • Availability

  • Thrombogenicity when incorporated with xenogeneic natural polymers.

  • Short off-shelf time and unavailability for acute procedures.