Table 1.
Morbidly Obese at Inclusion (no 46) |
Healthy Volunteers (no 46) |
Morbidly Obese 6 Months after Surgery (no 19) |
|
---|---|---|---|
Age (years, mean (SD)) | 43.6 (8.5) | 43.6 (8.6) | 45.7 (6.6) |
Gender (men/women; no (%)) | 2 (4%)/44 (96%) | 2 (4%)/44 (96%) | 0 (0%)/19 (100%) |
BMI kg/m2 (mean (SD)) | 41.9 (3.5) | 22.5 (1.5) | 30.6 (3.7) |
Diabetes (no (%)) | 4 (9%) | 0 (0%) | |
Metformin (no (%)) | 3 (7%) | 0 (0%) | |
Irritable bowel syndrome (no (%)) | 23 (50%) | 0 (0%) | |
IBS-D, IBS-M, IBS-C (no) 1 | 7/11/4 | ||
CRP (mean (SD)) | 7.0 (5.7) | n.a. | |
NNS (units/day) 2 (mean (SD)) | 8.7 (11.9) | n.a. | |
Zonulin (mean (SD)) | 68.3 (37.1) | n.a. | |
Operation: Bypass/Sleeve (no (%)) | 15 (79%)/4 (21%) |
1 IBS-D: irritable bowel syndrome—diarrhoea predominant, IBS-M: irritable bowel syndrome—mixed, IBS-C: irritable bowel syndrome—constipation predominant. 2 NNS = non-nutritive sweeteners. One unit = 100 mL beverage with NNS or two tablets/teaspoons of NNS.