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. 2021 Mar 23;13(3):1037. doi: 10.3390/nu13031037

Figure 7.

Figure 7

Modulation of the hepatic activities of enzymes involved in fatty acid biosynthesis by the diet. Mice were fed low-fat diet (LFD) supplemented with cellulose (LFDc, black bars) or inulin (LFDi, hatched black bars), or high-fat diet (HFD) supplemented with cellulose (HFDc, green bars) or inulin (HFDi, hatched green bars) for 11 weeks. (a) SCD1 activity corresponding to the ratio “product” (C16:1n-7 or C18:1n-9)/“precursor” (C16:0 or C18:0). (b) FADS1 activity corresponding to the ratio “product” (C20:4n-6)/“precursor” (C20:3n-6). (c) FADS2 activity corresponding to the ratio “product” (C18:3n-6)/“precursor” (C18:2n-6). (d) ELOVL3 activity corresponding to the ratio “product” (C24:1n-9)/“precursor” (C18:1n-9). (e) ELOVL5 activity corresponding to the ratio “product” (C20:5n-3 or C20:4n-6)/“precursor” (C18:3n-3 or C18:2n-6). (f) ELOVL2 and ELOVL5 activities corresponding to the ratio “product” (C22:5n-3 or C22:4n-6)/“precursor” (C20:5n-3 or C20:4n-6). (g) ELOVL6 activity corresponding to the ratio “product” (C18:0)/“precursor” (C16:0). Data are presented as mean ± SEM (n = 11–12 in each group). * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001.