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. 2021 Mar 23;10(3):342. doi: 10.3390/antibiotics10030342

Table 4.

Clinical and epidemiological characteristics of CHG-tolerant isolates vs. CHG-susceptible MSSA and MRSA isolates.

Characteristic Reduced Susceptibility to CHG
among MSSA Isolates (n = 98)
p-Value 1 Reduced Susceptibility to CHG
among MRSA Isolates (n = 92)
p-Value 1
Yes (n = 3) No (n = 95) Yes (n = 22) No (n = 70)
qac A/B presence 0.717 0.004 2
Yes 0 4 (100) 10 (47.6) 11 (52.4)
No 3 (3.2) 91 (96.8) 12 (16.9) 59 (83.1)
Mupirocin susceptibility <0.0001 0.161
Resistant 1 (50) 1 (50) 6 (37.5) 10 (62.5)
Sensitive 2 (2.1) 94 (97.9) 16 (21.1) 60 (78.9)
Mupirocin’s MIC (mg/L) 0.846 0.243
Mean 85.4 13.1 280.9 146.6
Median (Q1, Q3) 0.125 (0.094, 0.19) 0.22 (0.125, 776) 0.125 (0.101, 0.25)
pvl presence 0.532 0.152
Yes 0 11(100) 4 (14.3) 24 (85.7)
No 3 (3.4) 84 (96.6) 18 (28.1) 46 (71.9)
Sample source 0.960 0.009
Blood culture 1 (2.9) 33 (97.1) 13 (39.4) 20 (60.6)
Wounds 2 (3.1) 62 (96.9) 9 (15.3) 50 (84.7)

1 Chi-squared test, Mann-Whitney test. 2 Bold values indicate statistical significance.