Table 3.
Expression levels of Treg cell relevant factors in COVID-19 patients and control groups.
| Mild patients | Healthy controls | P value | Severe patients | Healthy controls | P value | Severe patients | Mild patients | P value | |
|---|---|---|---|---|---|---|---|---|---|
| FoxP3 | 0.64 ± 0.14 | 0.99 ± 0.11 | 0.0063 | 0.43 ± 0.13 | 0.99 ± 0.11 | 0.0002 | 0.43 ± 0.13 | 0.64 ± 0.14 | 0.02 |
| IL-10 | 0.43 ± 0.19 | 1.03 ± 0.09 | 0.0004 | 0.41 ± 0.21 | 1.03 ± 0.09 | 0.0001 | 0.41 ± 0.21 | 0.43 ± 0.19 | 0.08 |
| IL-35 | 0.56 ± 0.1 | 0.982 ± 0.08 | 0.0054 | 0.33 ± 0.32 | 0.982 ± 0.08 | 0.0005 | 0.33 ± 0.32 | 0.56 ± 0.1 | 0.06 |
| TGF-β | 0.49 ± 0.16 | 1.04 ± 0.04 | 0.0036 | 0.38 ± 0.14 | 1.04 ± 0.04 | 0.0001 | 0.38 ± 0.14 | 0.49 ± 0.16 | 0.03 |
Abbreviations: COVID-19, Coronavirus disease 2019; Treg, T-regulatory; FoxP3, forkhead box P3; IL, interleukin; TGF-β, transforming growth factor beta.