TABLE 1.

Common Measures and Domains for Assessing HRQOL in AYAs^a

Domain	MMQL Adolescent and Young Adult Forms	PedsQL 4.0 Generic and 3.0 Cancer Module	PCQL-32 and PCQL Modular	LAYA-SRQL	IOC-CS
For Ages:	13 to 20 and 21 to 45 Years	13 to 18, 18 to 25, and ≥25 Years	8 to 18 Years	18 to 39 Years	18 to 39 Years
Physical	Physical Body image	Physical functioning Pain and hurt Nausea Perceived physical appearance	Disease and treatment-related symptoms Physical Pain Nausea	Vitality Fertility	Body/health
Mental	Psychological Outlook on life Cognitive functioning	Emotional functioning Procedural anxiety Treatment anxiety Worry Cognitive problems	Psychological Cognitive functioning	Existential/spirituality Coping Cognition/memory	Personal growth Life challenges Thinking/memory problems
Social	Social Intimate relations	Social functioning Communication	Social	Relationship Dependence Intimacy/sexuality	Talking with parents Socializing
Other		School functioning		Health care Education/career	Health literacy Financial problems

Abbreviations: AYA, adolescent and young adult; HRQOL, health-related quality of life; IOC-CS, Impact of Cancer scale for childhood cancer survivors⁴⁸; LAYA-SRQL, Late Adolescence and Young Adulthood–Survivorship-Related Quality of Life scale⁴⁹; MMQL Adolescent, Minneapolis-Manchester Quality of Life instrument–Adolescent form⁵⁰; MMQL Young Adult, Minneapolis-Manchester Quality of Life instrument–Young Adult form⁵¹; PCQL Modular, Pediatric Cancer Quality of Life Inventory–Modular Approach⁵³; PCQL-32, Pediatric Cancer Quality of Life Inventory-32⁵²; PedsQL 3.0 Cancer Module, Pediatric Quality of Life Inventory Cancer Module⁵⁴; PedsQL 4.0 Generic, Pediatric Quality of Life Inventory Version 4.0 Generic Core Scales.⁵⁵

^aBold font indicates the presence of financial burden, body image, and fertility and/or parenthood dimensions captured by existing measures.