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. 2021 Mar 22;19(1):2276. doi: 10.18549/PharmPract.2021.1.2276

Table 2. Unadjusted and adjusted logistic regression analyses of factors associated with the acceptance of a COVID-19 vaccine among respondents in Russia (n = 876).

Variable n (%) Vaccine acceptance n (%) Unadjusted Adjusted
OR (95%CI) p-value aOR (95%CI) p-value
Gender
Female 651 (74.3) 240 (36.9) 1 1
Male 225 (25.7) 125 (55.6) 2.14 (1.57-2.91) <0.001 2.37 (1.41-4.00) 0.001
Age (years)
18-25 350 (40.0) 134 (38.3) 1 1
26-40 283 (32.4) 114 (40.3) 1.09 (0.79-1.50) 0.609 2.01 (0.57-7.11) 0.277
41-60 177 (20.3) 84 (47.5) 1.46 (1.01-2.10) 0.044 2.44 (0.70-8.46) 0.161
>60 64 (7.3) 32 (50) 1.61 (0.94-2.75) 0.080 1.39 (0.53-3.60) 0.503
Marital status
Single 483 (55.1) 199 (41.2) 1
Married 393 (44.9) 166 (42.2) 1.04 (0.80-1.37) 0.757
Education
Secondary and lower 184 (21.0) 81 (44) 1
Vocationalization 135 (15.4) 59 (43.7) 0.99 (0.63-1.55) 0.955
University 557 (63.6) 225 (40.4) 0.86 (0.62-1.20) 0.387
Urbanicity
Suburban/Rural 106 (12.1) 49 (46.2) 1
Urban 764 (87.2) 314 (41.1) 0.81 (0.54-1.22) 0.316
Smoking status
Never smoke 623 (71.1) 250 (40.1) 1 1
Former smoker 80 (9.1) 34 (42.5) 1.10 (0.69-1.77) 0.684 0.70 (0.30-1.62) 0.408
Current smoker 162 (18.5) 76 (46.9) 1.32 (0.93- 1.87) 0.119 1.46 (0.83-2.58) 0.194
Diagnosed with chronic diseases
No 609 (69.5) 255 (41.9) 1
Yes 252 (28.8) 105 (41.7) 0.99 (0.74-1.34) 0.956
Occupation category
Retired/Housewife/Student 446 (51.0) 177 (83.1) 1 1
General worker 290 (33.1) 124 (42.8) 1.14 (0.84-1.53) 0.408 0.57 (0.17-1.90) 0.363
Managerial 139 (15.9) 63 (45.3) 1.26 (0.86-1.85) 0.239 0.75 (0.22-2.58) 0.652
Healthcare related job
No 519 (59.2) 234 (45.1) 1 1
Yes 354 (40.4) 129 (36.4) 0.70 (0.53-0.92) 0.011 0.73 (0.44-1.21) 0.221
Job requiring interaction with lots of people
No 474 (54.1) 192 (40.5) 1
Yes 402 (45.9) 173 (43) 1.11 (0.85-1.45) 0.449
Positive COVID-19 status
No 765 (87.3) 333 (43.5) 1 1
Yes 75 (8.6) 27 (36) 0.73 (0.45-1.19) 0.210 0.65 (0.24-1.75) 0.394
Monthly income (1 thousand RUB)
<20 272 (31.1) 123 (45.2) 1.73 (0.99-3.03) 0.057 2.34 (1.05-5.25) 0.038
20-40 235 (26.8) 105 (44.7) 1.69 (0.96-2.99) 0.071 2.94 (1.32-6.57) 0.008
41-80 187 (21.3) 79 (42.2) 1.53 (0.85-2.75) 0.155 2.44 (1.08-5.51) 0.032
>80 68 (7.8) 22 (32.4) 1 1
Trust in the healthcare system
No 464 (53.0) 143 (30.8) 1 1
Yes 392 (44.7) 218 (55.6) 2.81 (2.13-3.72) <0.001 2.73 (1.76-4.24) <0.001
Risk Perception Score (%)
0 109 (12.4) 46 (42.2) 1 1
10-20 133 (15.2) 54 (40.6) 0.94 (0.56-1.57) 0.801 0.73 (0.33-1.65) 0.452
30-40 222 (25.3) 111 (50) 1.37 (0.86-2.17) 0.182 1.18 (0.56-2.48) 0.654
50-60 194 (22.1) 82 (42.3) 1.00 (0.62-1.61) 0.991 0.67 (0.32-1.42) 0.300
>60 182 (20.8) 67 (36.8) 0.80 (0.49-1.30) 0.362 0.67 (0.27-1.65) 0.383
Perceived benefits
Vaccination helps reduce the risk of virus infection
Disagree 634 (72.4) 171 (27) 1 1
Agree 242 (27.6) 194 (80.2) 10.94 (7.62-15.71) <0.001 8.80 (5.21-14.87) <0.001
Vaccination will ease complications of the disease
Disagree 624 (71.2) 170 (27.2) 1 1
Agree 252 (28.8) 195 (77.4) 9.14 (6.48-12.88) <0.001 10.46 (6.09-17.96) <0.001
The vaccine will help to provide long-term immunity
Disagree 544 (62.1) 175 (32.2) 1 1
Agree 332 (37.9) 190 (57.2) 2.82 (2.13-3.74) <0.001 2.73 (1.72-4.35) <0.001
Perceived barriers
Concern about possible side effects of vaccination
Disagree 352 (40.2) 178 (50.6) 1.84 (1.40-2.43) <0.001 1.65 (1.03-2.65) 0.036
Agree 524 (59.8) 187 (35.7) 1 1
Unproven vaccine safety and effectiveness
Disagree 337 (38.5) 193 (57.3) 2.86 (2.16-3.79) <0.001 2.55 (1.60-4.08) <0.001
Agree 539 (61.5) 172 (31.9) 1 1
Concern of affordability (high cost)
Disagree 688 (78.5) 282 (41) 1
Agree 188 (21.5) 83 (44.1) 1.14 (0.82-1.58) 0.436
Religious reasons
Disagree 854 (97.5) 353 (41.3) 1 1
Agree 22 (2.5) 12 (54.5) 1.70 (0.73-3.99) 0.220 8.08 (1.52-42.93) 0.014
The threat of COVID-19 has been exaggerated
Disagree 761 (86.9) 336 (44.2) 2.35 (1.50-3.66) <0.001 2.33 (1.05-5.16) 0.038
Agree 115 (13.1) 29 (25.2) 1 1
Afraid of injections
Disagree 833 (95.1) 356 (42.7) 2.82 (1.34-5.95) 0.007 2.66 (0.87-8.19) 0.088
Agree 43 (4.9) 9 (20.9) 1 1
Belief in natural or traditional remedies
Disagree 833 (95.1) 352 (42.3) 1.69 (0.87-3.28) 0.123 7.29 (1.88-28.30) 0.004
Agree 43 (4.9) 13 (30.2) 1 1
I’m young and healthy
Disagree 783 (89.4) 333 (42.5) 1.41 (0.90-2.21) 0.135 3.60 (1.41-9.18) 0.007
Agree 93 (10.6) 32 (34.4) 1 1
I don’t need the vaccine because I do all the right things (hand washing and wearing masks, gloves)
Disagree 710 (81.1) 303 (42.7) 1.25 (0.88-1.77) 0.211 1.23 (0.67-2.24) 0.507
Agree 166 (18.9) 62 (37.3) 1 1
The best way is to let nature take its course
Disagree 738 (84.2) 329 (44.6) 2.28 (1.52-3.42) <0.001 2.57 (1.24-5.34) 0.011
Agree 138 (15.8) 36 (26.1) 1 1
Cues to action
Verified safety and effectiveness
Disagree 322 (36.8) 123 (38.2) 1 1
Agree 554 (63.2) 242 (43.7) 1.26 (0.95-1.66) 0.113 1.80 (1.08-3.00) 0.025
Taken by many of the population
Disagree 660 (75.3) 256 (38.8) 1 1
Agree 216 (24.7) 109 (50.5) 1.61 (1.18-2.19) 0.003 1.85 (1.12-3.08) 0.017
Recommended by a trusted doctor
Disagree 702 (80.1) 273 (38.9) 1 1
Agree 174 (19.9) 92 (52.9) 1.76 (1.26-2.46) 0.001 1.02 (0.56-1.86) 0.951
Mandatory vaccination is required at the workplace
Disagree 765 (87.3) 310 (40.5) 1 1
Agree 111 (12.7) 55 (49.5) 1.44 (0.97-2.15) 0.072 2.76 (1.37-5.58) 0.005