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. 2021 Mar 20;58(8):1101–1110. doi: 10.1007/s00592-021-01701-1

Table 1.

Characteristics of included studies

Study Country Study design DM group Non-DM group
No Age Sex, male No Age Sex, male
Acharya D et al. [12] Korea Multi-center cross-sectional study 55 69.8 ± 13.5 20 (36.4%) 269 51.9 ± 21.4 115 (42.8%)
Al-Salame et al. [13] France Observational cohort 115 72.6 ± 3.3 73 (62.6%) 317 72.3 ± 4.2 165 (52.1%)
Alzaid et al. [14] France Observational cohort 30 64.8 ± 6.6 23 (76.7%) 15 63.3 ± 7.2 8 (53.3%)
Chung SM. et al. [15] South Korea Retrospective cohort study 29 66.3 ± 8.9 14 (48.3%) 81 53.5 ± 17.9 34 (24.0%)
Conway J. et al. [16] UK Retrospective case series 16 NS 9 (56.3%) 55 NS 32 (58.2%)
Fox T. et al. [17] USA Retrospective observational study 166 66.42 ± 12.67 86 (51.8%) 189 66.03 ± 15.46 88 (46.6%)
Guan Wj. et al. [18] China Multi-center retrospective case study 130 61.2 ± 13.4 76/129 (58.9%) 1460 47.8 ± 16.1 828/1449 (57.1%)
Kim MK. et al. [19] Korea Multi-center, retrospective, observational study 235 68.3 ± 11.9 106 (45.1%) 235 69.7 ± 12.4 95 (40.4%)
Liang JJ. et al. [20] China Retrospective study 55 62.4 ± 7.7 27 (49.1%) 76 63.3 ± 8.3 43 (56.6%)
Liu D. et al. [21] China Retrospective observational study 19 60.3 ± 11.9 10 (52.6%) 76 46.5 ± 17.2 36 (47.4%)
Liu Z. et al. [22] China Retrospective observational study 139 64.5 ± 10.0 66 (47.5%) 795 61.6 ± 14.5 388 (48.8%)
Saeed O. et al. [23] USA Retrospective study 2266 67.9 ± 12.8 1189 (52.5%) 1986 61.1 ± 17.6 1066 (53.7%)
Shang J. et al. [24] China Retrospective, single-center cohort study 84 NS 42 (50.0%) 500 NS 235 (47.0%)
Soliman A. et al. [25] Qatar Retrospective study 56 52.1 ± 12.67 NS 243 36.22 ± 11.43 NS
Wu D. et al. [26] China Retrospective study 16 43.5 ± 17.8 8 (50.0%) 47 51.0 ± 12.6 25 (53.1%)
Wu J. et al. [27] China Retrospective study 22 52.55 ± 13.70 16 (72.73) 44 47.98 ± 15.11 28 (63.64%)
Xu Z. et al. [28] China Retrospective study 114 65.5 ± 2.7 62 (54.4%) 250 63.3 ± 3.5 144 (57.6%)
Zhang Y. et al. [29]a China Retrospective study 63 64.5 ± 4.0 38 (60.3%) 195 63.3 ± 2.5 100 (51.3%)
Zhang Y. et al. [30]b China Retrospective study 61 65.6 ± 11.4 33 (54.1%) 84 59.4 ± 16.0 41 (48.8%)
Summary characteristics 3671 66.9 ± 12.5 1898/3614 (52.5%) 6917 67.5 ± 17.5 3471/6663 (52.1%)

DM Diabetes mellitus; NS Not specified