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. Author manuscript; available in PMC: 2021 May 30.
Published in final edited form as: Nat Mater. 2020 Nov 30;20(4):548–559. doi: 10.1038/s41563-020-00849-5

Extended Data Figure 8: ECM Stiffness for individual specimens.

Extended Data Figure 8:

(a) Scatter plot showing mean and individual values of atomic force microscopy (AFM) microindentation measurements of individual human samples categorized as normal breast tissue (black circles) or invasive ductal carcinoma (IDC; red squares). (b) Scatter plot showing mean and individual values of AFM microindentation measurements of individual mouse mammary tumors from doxycycline treated MMTV-PyMT+/−; Col1a1-tTA+/−; TetO-mLox control mice (DOX-ind PyMT Con; black circles) or water treated mice overexpressing stromal Lox (Water PyMT Lox OX; red squares). (c) Scatter plot showing mean and individual values of AFM microindentation measurements of individual mouse mammary gland tumors from 8-week-old IgG1 treated (IgG Control; red squares) and anti-CSF1 treated (aCSF1 Ab; black circles) PyMT tumors.