Table 1, online only.
Characteristics of PCCC T21 cohort
| Total | Death at 1st surg. hosp | Long-term survival | Confirmed death | P value | |
|---|---|---|---|---|---|
| (n = 3,571) | (n = 195) | (n = 2,990) | (n = 386) | ||
| Age 1st surg N (%) | <0.001 | ||||
| < 28 days | 134 (3.8) | 28 (14.4) | 79 (2.6) | 27 (7.0) | |
| 28–364 days | 2,587 (72.4) | 145 (74.4) | 2,173 (72.7) | 269 (69.7) | |
| 1–5 yr | 685 (19.2) | 17 (8.7) | 596 (19.9) | 72 (18.6) | |
| 6–20 yr | 165 (4.6) | 5 (2.6) | 142 (4.7) | 18 (4.7) | |
| Age 1st surgery (yrs) median, (IQR) | 0.51 (0.33–0.94) | 0.40 (0.20–0.65) | 0.52 (0.34–0.98) | 0.51 (0.28–0.90) | <0.001 |
| Sex N (%) | 0.326 | ||||
| Male | 1,725 (48.3) | 91 (46.7) | 1,434 (48.0) | 200 (51.8) | |
| Female | 1,846 (51.7) | 104 (53.3) | 1,556 (52.0) | 186 (48.2) | |
| Era 1st surg N (%) | <0.001 | ||||
| Early: 1982–1992 | 1,092 (30.6) | 89 (45.6) | 837 (28.0) | 166 (43.0) | |
| Middle: 1993–1997 | 1,103 (30.9) | 54 (27.7) | 937 (31.3) | 112 (29.0) | |
| Late: 1999–2003 | 1,376 (38.5) | 52 (26.7) | 1,216 (40.7) | 108 (28.0) | |
| Palliation N (%) | 313 (8.8) | 35 (17.9) | 182 (6.1) | 96 (24.9) | <0.001 |
| Complexity N (%) | <0.001 | ||||
| Mild | 1,191 (33.4) | 25 (12.8) | 1,085 (36.3) | 81 (21.0) | |
| Moderate | 2,124 (59.5) | 131 (67.2) | 1,749 (58.5) | 244 (63.2) | |
| Severe | 256 (7.2) | 39 (20.0) | 156 (5.2) | 61 (15.8) | |
| ECLS at 1st surgical hospitalization N (%) | 15 (0.4) | 10 (5.1) | 5 (0.2) | 0 | <0.001 |
| PPM at 1st surgical hospitalization N (%) | 75 (2.1) | 3 (1.5) | 57 (1.9) | 15 (3.9) | 0.050 |
| Cardiac Dx N (%) | <0.001 | ||||
| ASD | 239 (6.7) | 2 (1.0) | 219 (7.3) | 18 (4.7) | |
| Incomplete AVC | 324 (9.1) | 4 (2.0) | 289 (9.7) | 31 (8.0) | |
| VSD simple | 952 (26.7) | 23 (11.8) | 866 (29.0) | 63 (16.3) | |
| VSD complex | 60 (1.7) | 2 (1.0) | 54 (1.8) | 4 (1.0) | |
| CAVC | 1,570 (44.0) | 116 (59.5) | 1,268 (42.1) | 186 (48.2) | |
| CAVC+ arch obstr | 62 (1.7) | 13 (6.7) | 32 (1.1) | 17 (4.4) | |
| TOF | 205 (5.7) | 13 (6.7) | 162 (5.4) | 30 (7.8) | |
| CAVC + TOF | 159 (4.5) | 22 (11.3) | 100 (3.3) | 37 (9.6) | |
Given are number (N) and percent (%) by column for categorical variables, median and interquartile range (IQR) for continuous variable. P values represent differences between death at first surgical hospitalization, alive at follow-up, and confirmed death groups using Chi-square or Fisher’s exact test as appropriate for categorical variables, Kruskal-Wallis test for continuous variables. Surg.hosp = surgical hospitalization; ECLS = extracorporeal life support; PPM = permanent pacemaker; Dx = diagnosis; ASD = atrial septal defect; Incomplete AVC = partial or transitional atrioventricular canal; VSD = ventricular septal defect; CAVC = common atrioventricular canal; arch obstr = aortic arch obstruction including coarctation or interrupted aortic arch; TOF = tetralogy of Fallot.