FIGURE 7.

SC inhibited VEGF-induced phosphorylation of ERK1/2, Akt, and p38-MAPK in HRMECs.(A) The cells were first incubated with or without SC (2.5 μM) for 8 h and then treated with VEGF(10 ng/ml) for 24 and 48 h. The phosphorylation and total ERK1/2, AKT, and p-38 MAPK were analysed by Western blot. (B–D) The relative density ratio of p-AKT to AKT, p-ERK to ERK and p-p38-MAPK to p38-MAPK. *p < 0.05, compared to the untreated group at the corresponding time point. #p < 0.05 compared to the VEGF-treated group.