TABLE 2.
Allele frequencies of kidney dysfunction-related gene variants.
| Gene | dbSNP ID | SNP position | Allele change | MAF | Proven disease associations (Ensembl) |
| UNCX | rs10277115 | 7:1245559 | A > T | 0.16 | Renal function related trait |
| APOL1 (G1) | rs73885319 | 22:36265860 | T > G | 0.13 | Renal function related trait |
| APOL1 (G2) | rs71785313 | 22:36266000 | TTATAA > Deletion | 0.082 | Renal function related trait |
| A1CF | rs10994860 | 10:50885664 | C > T | 0.24 | Glomerular filtration rate |
| DAB2 | rs11959928 | 5:39397030 | T > A | 0.32 | Chronic kidney disease |
| SYPL2 | rs12136063 | 1:109471548 | G > A | 0.29 | Glomerular filtration rate |
| GCKR | rs1260326 | 2:27508073 | C > T | 0.057 | - |
| KCNQ1 | rs163160 | 11:2768725 | A > G | 0.057 | Glomerular filtration rate |
| SLC22A2 | rs2279463 | 6:160247357 | A > G | 0.23 | Chronic kidney disease |
| NFKB1 | rs228611 | 4:102640552 | G > A | 0.228 | Glomerular filtration rate |
| IGFBP5 | rs2712184 | – | C > A | 0.46 | – |
| TFDP2 | rs347685 | 3:142088295 | A > C | 0.248 | Chronic kidney disease |
| UMOD | rs4293393 | 16:20353266 | A > G | 0.227 | Chronic kidney disease |
| TMEM60 | rs6465825 | 7:77787122 | C > T | 0.45 | Chronic kidney disease |
| WNT7A | rs6795744 | 3:13865353 | G > A | 0.191 | Glomerular filtration rate |
| PTPRO | rs7956634 | 12:15168260 | C > T | 0.45 | Glomerular filtration rate |
| NFATC1 | rs8091180 | 18:79404243 | G > A | 0.068 | Glomerular filtration rate |
| SKIL | rs9682041 | 3:170374114 | T > C | 0.274 | Glomerular filtration rate |