TABLE 3.
Blood pressure, clinical, and haematological variables, and genetic variants associated eGFR and Crude albuminuria.
| eGFR (ml/min/1.73 m2) | Effect size (SE) | Mean variation explained (%) | P-values |
| SBP | −15.01547 (7.51850) | 40.55 | 0.04674 |
| VOC | 0.79123 (0.35834) | 21.73 | 0.02802 |
| Hb | 3.11861 (1.40541) | 16.44 | 0.02725 |
| MCV (fl) | 0.68573 (0.15854) | 1.90 | 2.09130e–05 |
| HbF | 1.62340 (0.32960) | 1.13 | 1.40989e–06 |
| Platelet | 0.05052 (0.01497) | 0.28 | 8.35290e–04 |
| Granulocytes | 2.06830 (0.76779) | 0.12 | 7.47090e–03 |
| Lymphocytes | 2.12071 (0.97584) | 0.08 | 0.03057 |
| rs12136063* | 0.57907 (0.28487) | 11.04 | 0.04208 |
| rs10994860* | −0.69852 (0.30075) | 0.18 | 0.02020 |
| rs73885319* | 0.890305 (0.44638) | 0.97 | 0.04610 |
| Crude albuminuria (mg/dl) | |||
| BMI | 0.01872 (0.00596) | 45.34 | 1.87777e–03 |
| MCV (fl) | 0.01273 (0.00121) | 1.22 | 1.17630e–07 |
| Transfusion | 0.12406 (0.05602) | 0.23 | 0.02759 |
| Hb* | −0.28340 (0.11040) | 0.19 | 0.0103 |
| rs6795744* | −0.59520 (0.28580) | 3.70 | 0.03730 |
| rs6465825* | −0.46910 (0.20690) | 0.65 | 0.02340 |
| rs71785313 | −0.12686 (0.06086) | 0.10 | 0.03803 |
Effect provides an indication on the influence of a given factor on the phenotype under consideration and mean variation explained the average contribution of a specific factor to the phenotype. SE stands for standard error and * indicates that the association was inferred from logistic model.