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. 2021 Mar 15;12:510350. doi: 10.3389/fgene.2021.510350

Table 3.

Stratification analysis of susceptibility in KD patients.

Variables rs1751034 (IVIG-R/IVIG-S) p OR (95% CI) pa Adjusted OR (95% CI) Adjusted pb combined analysis (IVIG-R/IVIG-S) p OR (95% CI) pa Adjusted OR (95% CI) Adjusted pb
TT/TC CC 0–2 3–6
Age, months
≤60 118/545 11/19 0.0172 2.67 (1.24–5.77) 0.0122 2.65 (1.23–5.71) 0.0133 69/384 60/180 0.0020 1.86 (1.26–2.74) 0.0018 1.86 (1.26–2.74) 0.0018
>60 18/45 1/3 0.8764 0.83 (0.08–8.56) 0.8780 0.87 (0.08–8.96) 0.9036 15/25 4/23 0.0375 0.29 (0.08–1.00) 0.0503 0.29 (0.08–1.01) 0.0509
Gender
Male 90/404 7/13 0.0821 2.42 (0.94–6.23) 0.0677 2.35 (0.91–6.08) 0.0775 54/279 43/138 0.0392 1.61 (1.03–2.52) 0.0378 1.62 (1.03–2.55) 0.0354
Female 46/186 5/9 0.1816 2.25 (0.72–7.02) 0.1640 2.32 (0.74–7.31) 0.1517 30/130 21/65 0.2999 1.40 (0.74–2.63) 0.2969 1.47 (0.78–2.78) 0.2373
a

Two-sided χ2 test for distributions between Kawasaki disease patients with IVIG resistance and IVIG sensitivity.

b

Adjusted for age and gender, stratified by gender (adjusted for age), and stratified by age (adjusted for gender).

Bold values indicate value of p less than 0.05.