Table 3.
Stratification analysis of susceptibility in KD patients.
| Variables | rs1751034 (IVIG-R/IVIG-S) | p | OR (95% CI) | pa | Adjusted OR (95% CI) | Adjusted pb | combined analysis (IVIG-R/IVIG-S) | p | OR (95% CI) | pa | Adjusted OR (95% CI) | Adjusted pb | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TT/TC | CC | 0–2 | 3–6 | |||||||||||
| Age, months | ||||||||||||||
| ≤60 | 118/545 | 11/19 | 0.0172 | 2.67 (1.24–5.77) | 0.0122 | 2.65 (1.23–5.71) | 0.0133 | 69/384 | 60/180 | 0.0020 | 1.86 (1.26–2.74) | 0.0018 | 1.86 (1.26–2.74) | 0.0018 |
| >60 | 18/45 | 1/3 | 0.8764 | 0.83 (0.08–8.56) | 0.8780 | 0.87 (0.08–8.96) | 0.9036 | 15/25 | 4/23 | 0.0375 | 0.29 (0.08–1.00) | 0.0503 | 0.29 (0.08–1.01) | 0.0509 |
| Gender | ||||||||||||||
| Male | 90/404 | 7/13 | 0.0821 | 2.42 (0.94–6.23) | 0.0677 | 2.35 (0.91–6.08) | 0.0775 | 54/279 | 43/138 | 0.0392 | 1.61 (1.03–2.52) | 0.0378 | 1.62 (1.03–2.55) | 0.0354 |
| Female | 46/186 | 5/9 | 0.1816 | 2.25 (0.72–7.02) | 0.1640 | 2.32 (0.74–7.31) | 0.1517 | 30/130 | 21/65 | 0.2999 | 1.40 (0.74–2.63) | 0.2969 | 1.47 (0.78–2.78) | 0.2373 |
Two-sided χ2 test for distributions between Kawasaki disease patients with IVIG resistance and IVIG sensitivity.
Adjusted for age and gender, stratified by gender (adjusted for age), and stratified by age (adjusted for gender).
Bold values indicate value of p less than 0.05.