TABLE 2.
Comparison of the variables between HELLP patients with different severities of AKI.
| Variables | AKI stage 1 (n = 28) | AKI stage 2 (n = 19) | AKI stage 3 (n = 18) | p-value |
| Age (years) | 31.58 ± 4.86 | 30.82 ± 4.99 | 31.25 ± 4.59 | 0.854 |
| History of hypertension | 4 (14.3%) | 2 (10.5%) | 2 (11.1%) | 0.913 |
| Multipara | 15 (53.6%) | 7 (36.8%) | 6 (33.3%) | 0.324 |
| Cesarean delivery | 25 (89.3%) | 19 (100%) | 18 (100%) | 0.845 |
| Eclampsia | 7 (25%) | 4 (21.1%) | 4 (22.2%) | 0.947 |
| Bleeding (>400 ml) | 11 (39.3%) | 4 (21.1%) | 5 (27.8%) | 0.392 |
| Infection | 6 (21.4%) | 3 (15.8%) | 3 (16.7%) | 0.864 |
| Perinatal death | 5 (17.9%) | 3 (15.8%) | 4 (22.2%) | 0.875 |
| Maternal death | 1 (3.6%) | 1 (5.3%) | 2 (11.1%) | 0.573 |
| SBP ≥ 160 mmHg | 18 (64.3%) | 13 (68.4%) | 12 (66.75) | 0.956 |
| DBP ≥ 110 mmHg | 17 (60.7%) | 10 (52.6%) | 13 (72.2%) | 0.469 |
| Onset time of HELLP (weeks) | 31.81 ± 3.24 | 30.86 ± 3.40 | 30.75 ± 3.17 | 0.485 |
| Lowest platelet count (×109 cell/L) | 50.42 ± 13.12 | 34.80 ± 10.98 | 34 ± 8.88 | <0.001 |
| Lowest hemoglobin (g/L) | 89.59 ± 12.05 | 72.96 ± 10.30 | 69.73 ± 8.06 | <0.001 |
| LDH (U/L) | 835.67 ± 222.79 | 1115.69 ± 305.19 | 1397.48 ± 38.89 | <0.001 |
| AST (U/L) | 132.49 ± 42.31 | 154.16 ± 39.19 | 134.48 ± 38.89 | 0.148 |
| ALT (U/L) | 201.89 ± 60.77 | 191.82 ± 70.45 | 161.17 ± 74.12 | 0.207 |
| Bilirubin (μmol/L) | 29.07 ± 13.32 | 49.06 ± 32.02 | 86.42 ± 41.88 | <0.001 |
| Serum creatinine (μmol/L) | 116.18 ± 19.86 | 236.60 ± 110.61 | 408.41 ± 61.13 | <0.001 |
SBP, systolic blood pressure; DBP, diastolic blood pressure; LDH, lactate dehydrogenase; and AST, aspartate transaminase.