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. 2021 Mar 15;11:610952. doi: 10.3389/fonc.2021.610952

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Copyright © 2021 Mouri, Kaira, Yamaguchi, Hashimoto, Miura, Shiono, Shinomiya, Akagami, Imai, Kobayashi and Kagamu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan–Meier survival curves of PFS and OS according to ANA positivity in the low and high cohorts. PFS (A) and OS (B) when a positive ANA cutoff of 1:40 was used, PFS (C) and OS (D) when a positive ANA cutoff of 1:80 was used. Survival analysis with ICI treatment: no significant difference in the PFS and OS was observed between the ANA-positive and ANA-negative patients or high and low ANA titer cohorts. PFS, progression-free survival; OS, overall survival; ANA, anti-nuclear antibody.