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. 2021 Mar 17;21(5):492. doi: 10.3892/etm.2021.9923

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Inhibition of TGF-β1 attenuated the cell migration induced by miR-29b inhibition. (A) Expression level of TGF-β1 in VSMCs transfected with or without TGF-β1 detected by RT-qPCR. (B) MTT assay of VSMCs transfected with miR-29b inhibitor with or without TGF-β1 siRNA. (C) Transwell assay of VSMCs transfected with miR-29b inhibitor with or without TGF-β1 siRNA. (D) MTT assay of VSMCs transfected with miR-29b mimic with or without TGF-β1 treatment. (E) Transwell assay of VSMCs transfected with miR-29b mimic with or without TGF-β1 treatment. ^*P<0.05 vs. control, n=6. Ctrl, control; miR, microRNA; mut, mutant; siRNA, small interfering RNA; NC, negative control; TGF-β1, transforming growth factor β1; VSMCs, vascular smooth muscle cells; WT, wild-type.