Figure 2.

Enrichment of pooled human faecal filtrates in the presence of 100 individual bacterial strains recovers hundreds of viral genomic fragments. (A) Compositional bar charts reflecting relative abundance of individual viral genomic contigs (randomly coloured) in enriched and non-enriched original pooled faecal filtrates (located at arrow starts). Samples are grouped by faecal pool used for enrichment (“A”, “B”, or “C”) and ordered by fraction of reads aligned to viral contigs (high to low). Black segments represent fractions of reads aligned to contigs of non-viral origin. Sample labelled with black dot is a blank MDA amplification control. (B) distribution of contigs by length and sequence coverage, overlayed by viral taxonomic assignment data. (C) PCoA ordination of samples based on Spearman’s rank correlations of relative abundance of viral contigs.