Table 2.

Details of the families in which the c.67G>C, p.(Gly23Arg) variant was found

Family number	Total number of family members at risk*	Carriers†	50% chance of carriership	25% chance of carriership	Proven non-carriers	No. of PDAC cases in carriers† and possible carriers (of which validated‡)
1	11	7	4	0	3	0 (−)
2	56	9	17	30	5	3 (1)
3	44	11	19	14	7	1 (1)
4	26	9	7	10	6	0 (−)
5	8	6	2	0	9	4 (2)
6	53	24	21	8	16	2 (0)
7	19	6	7	6	0	1 (1)
8	14	9	5	0	5	0 (−)
9	20	3	8	9	1	1 (0)
Total	251	84	90	77	52	12

*Proven non-carriers excluded.

†Includes proven and obligate carriers.

‡Through medical records and/or pathology reports.

PDAC, pancreatic ductal adenocarcinoma.