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SV AUC of SEC-fractionated VWF/fVIII complexes. SEC Samples A–E in HBS/Ca Buffer were centrifuged at 45,400g. A–E, absorbance scans at 280 nm. Curves represent fits to the continuous c(s) distribution model in SEDFIT. Only every other data point is shown for clarity. The root-mean-square deviations of the fits ranged from 0.0040 to 0.0045. F, c(s) distributions derived from the fitted data.
