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(A) Effect on body weight (B) food intake and (C) Representative infrared thermal images (D) BAT temperature (E) rectal temperature (F) glucose tolerance test and (G) area under the curve (H) insulin tolerance test and (I) area under the curve in female mice fed chow diet that received AAV8-hSyn-shSIRT3-DIO-GFP or AAV8-hSyn-DIO-GFP scrambled viruses in the POMC neurons. Values are mean ± SEM of 4–7 animals per group
