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(A) Body weight of rats under different nutritional status (fed, fast 48 h, refed 24 h) under standard diet. (B) Protein levels of SIRT3 in the ARC of rats under different nutritional status (fed, fast 48 h, refed 24 h). (C) Body weight gain of DIO mice. (D) Protein levels of SIRT3 in the MBH of DIO mice. Values are mean ± SEM of 8 animals per group. *P ≤ 0.05, **P ≤ 0.01 vs controls (Paired t-test and one-way ANOVA).
