Table 1.

Mechanical circulatory support (MCS) devices—characteristics

	VA-ECMO	Impella family					TandemHeart	ProtekDuo
		Impella 2.5	Impella CP	Impella 5.0/LD	Impella 5.5	Impella RP
Access	Percutaneous, femorala (arterial, venous)	Percutaneous, femorala	Percutaneous, femorala	Surgical, axillary/femoral or ascending aorta	Surgical, axillary/femoral or ascending aorta	Percutaneous, femoral vein	Percutaneous, transseptal	Right internal jugular
Mechanism	RA → aorta (oxygenation)	LV → aorta	LV → aorta	LV → aorta	LV → aorta		LA → aorta	RA → PA (±oxygenation)
Output (max)	5.0–7.0 L/min	2.5 L/min	3.7 L/min	5.0 L/min	5.5 L/min	4.6 L/min	5 L/min	4.5 L/min
Cannula size	15–23 arterial 19–28 venous	12F	14F	21F	21F	22F	15–17 arterial 21 venous	16–29F
Cardiac power	↑↑↑	↑	↑↑	↑↑↑	↑↑↑	↑↑	↑↑	↑↑
Afterload	↑↑↑	↓	↓	↓	↓	↓	↑	↑
Coronary perfusion	—	↑	↑	↑↑	↑↑	—	—	—

LV, left ventricle; PA, pulmonary artery; RA, right atrium.

^aOccassionally axillary.