. Author manuscript; available in PMC: 2021 Mar 29.

Published in final edited form as: Am J Emerg Med. 2018 Sep 27;37(7):1285–1288. doi: 10.1016/j.ajem.2018.09.035

Table 4.

Comparison of diagnostic parameters of standard (230 ng/ml) and both age-adjusted D-dimer thresholds for patients >50 [(Age × 5 ng/ml) and ((Age × 5) − 20 ng/ml)].

Diagnostic parameters	230 threshold	Age × 5 if age > 50 threshold	(Age × 5) − 20 if age > 50 threshold
Sensitivity (%) (95%CI)	99.8 (98.6–100)	95.8 (93.3–97.5)	97.0 (94.8–98.4)
Specificity (%) (95% CI)	16.7 (15.6–17.8)	34.1 (32.7–35.5)	27.9 (26.6–29.2)
PPV (%) (95% CI)	9.7 (8.8–10.7)	11.6 (10.5–12.7)	10.8 (9.8–11.9)
NPV (%) (95% CI)	99.9 (99.3–100)	98.9 (98.2–99.4)	99.0 (98.3–99.5)

CI; Confidence interval.