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. Author manuscript; available in PMC: 2021 Mar 29.
Published in final edited form as: Kidney Int. 2011 Jan 26;79(8):861–870. doi: 10.1038/ki.2010.527

Figure 7 |. Effect of postischemic geranylgeranylacetone (GGA) treatment on renal function and histology after renal pedicle occlusion (RPO).

Figure 7 |

(a) Serial blood urea nitrogen (BUN) at baseline and on days 1–4 in Hsp70+/+ mice subjected to 35 min of bilateral RPO. Mice were treated with GGA (800 mg/kg intraperitoneal (i.p.) was administered immediately after 35 min of bilateral RPO and again after 18 h of recovery) vs vehicle alone; ∇ indicates animal death; inset shows the effect of GGA postischemia on heat shock protein 70 (Hsp70) content; *P<0.05 for GGA treatment vs vehicle alone; n = 6. (b) Representative renal histology in the presence of vehicle vs GGA; tissue sections stained with hematoxylin and eosin; original magnification ×400.