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. 2021 Mar 16;13:93. doi: 10.1007/s40820-021-00611-9

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 12 — SEM image of the pyramid (a) and cone-shaped MNs (b). c A single-needle compression test that breaks around 225 mN during compression. d Fracture force of all subgroups of the pyramid and the cone-shaped MN fabricated by micromolding. e Hematoxylin and eosin images of human cadaver skin treated with cone-shaped silk MN: (i) MN loaded with microparticles and no post-treatment, (ii) MN with no microparticles and post-treatment with water vapor and (iii) MN loaded with microparticles and post-treated with water vapor. Reprinted from Ref. [184] with permission from Wiley