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. Author manuscript; available in PMC: 2021 Mar 29.
Published in final edited form as: J Cell Physiol. 2018 Aug 21;234(4):3948–3960. doi: 10.1002/jcp.27209

Figure 2.

Figure 2.

Migration of glioma cells from microtumors grown in collagen hydrogels. (A–C) Images of tumor cell migration in non-crosslinked collagen hydrogel. (D–F) Images of tumor cell migration in crosslinked collagen hydrogel. Microtumors formed by mixing tumor cells with non-crosslinked collagen solution. Scale bar: 400 μm. (A’–F’) Magnified images of insets indicated in (A–F). (G, H) Quantification of glioma cell migration from microtumors formed by non-crosslinked collagen or crosslinked collagen. *p < 0.05, compared with cells in hydrogels crosslinked with 0.5 mM and 1 mM 8S-StarPEG at same time point. ^p < 0.05, compared with cells in hydrogels crosslinked with 1 mM 8S-StarPEG at same time point.