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. Author manuscript; available in PMC: 2021 Mar 29.
Published in final edited form as: J Pathol. 2020 Sep 26;252(4):371–383. doi: 10.1002/path.5531

Figure 1.

Figure 1.

Cathelicidin dysregulation in alcohol-fed animals and ALD patients. (A) Alcohol-induced changes in Camp expression in different organs. PF, pair-fed; AF, alcohol-fed. (B) CRAMP protein immunoblotting of liver and spleen tissues. The bands are composite images of selected bands, and the corresponding GAPDH controls are shown. (C) Serum CRAMP protein levels. Data are expressed as mean SEM (n = 5–9). (D) Hepatic CAMP mRNA expression and (E) plasma LL-37 levels in ALD patients and healthy controls (HC). Data are expressed as mean SEM (n = 5–16). (F) Hepatic CAMP expression correlates with HIF1A and VDR expression in ALD patients.