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. 2021 Mar 20;7(1):18. doi: 10.3390/ijns7010018
NBS Newborn screening
IEM Inborn errors of metabolism
QNGM Quebec Network of Genetic Medicine
DBS Dried blood spot
DUS Dried urine spot
TLC Thin layer chromatography
Triple H Hyperornithinemia-hyperammonemia-homocitrullinuria
QNSP Quebec Neuroblastoma Screening Project
NIH National Institutes of Health
HVA Homovanillic acid
VMA Vanillylmandelic acid
QCs Quality controls
MS/MS Tandem mass spectrometry
LC-MS/MS Liquid chromatography-tandem mass spectrometry
CID Collision-induced dissociation
IS Internal standard
REB Research Ethics Board
CIUSSSE-CHUS Centre intégré universitaire de santé et de services sociaux de l’Estrie-Centre hospitalier universitaire de Sherbrooke
CMMA Combined malonic and methylmalonic aciduria
ASA Argininosuccinic aciduria
HCl Hydrochloric acid
IQA Internal quality assurance
ERNDIM European Research Network for Evaluation and Improvement of Screening, Diagnosis, and Treatment of Inborn Errors of Metabolism
LOQ Limit of quantitation
UHPLC-MS/MS Ultra-high performance liquid chromatography tandem mass spectrometry
MRM Multiple reaction monitoring
RRF Relative Response Factor
LOD Limits of detection
BSTFA N,O-Bis(trimethylsilyl)trifluoroacetamide