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Inhibition of Syk by R406 reduces TNF-α-induced inflammatory cytokine production in PTECs. ELISA with quantitative analysis on protein expression of (A) IL-6, (B) IL-8 and (C) ICAM-1 in culture supernatant from PTECs incubated with control medium, TNF-α and TNF-α pretreated with R406. *p < 0.05; **p < 0.01 and ***p < 0.001 between groups as indicated.
