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. 2021 Mar 10;12:620659. doi: 10.3389/fgene.2021.620659

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Copyright © 2021 Leurs, Martinand-Mari, Ventéo, Haitina and Debiais-Thibaud.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bgp gene expression on sections of late developing embryos of the small-spotted catshark Scyliorhinus canicula. (A–D) Bgp in situ hybridization: general (A) and closer (B–D) views on transverse sections of a 7.7 cm long embryo. (E) Bgp in situ hybridization on a parasagittal section of the Meckel’s cartilage of a hatchling embryo with developing teeth [dotted line separates the epithelial (e) and mesenchymal (m) compartments of teeth]. (F) HES staining of a comparable zone to (D). Expression detected in nerve root (B), cells surrounding ceratotrichiae (open arrowhead in C), mesenchymal cells of scale placodes (filled arrowhead in C), and mesenchyme of mature (dentin deposition) tooth buds (E), connective tissue at muscle attachment (black arrow in D,F) and at the tip of vasculature in gills (open arrow in D,F). Mc, Meckel’s cartilage; nc, notochord; nt, neural tube; vr, nerve root. Scales are in μm.