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. 2021 Mar 15;9:647702. doi: 10.3389/fcell.2021.647702

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Copyright © 2021 Chen, Liang, Yi, Fan, Chen, Zhang and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of the YTHDF1 targets in GC cells. (A) Heatmap of DEGs identified by RNA-seq. (B) GO enrichment analysis of DEGs. (C–G) GSEA plots showing the pathways of DEGs enriched by YTHDF1 were involved in GC cells. (H) Metagene profiles of m⁶A enrichment across mRNA transcriptome in BGC-823 cells. (I) The m⁶A motif detected by the DREME motif analysis with m⁶A-seq results. (J) The distribution of m⁶A peaks on different chromosomes. DEGs, differentially expressed genes; GC, gastric cancer; GO, Gene ontology; GSEA, gene set enrichment analysis. ***P < 0.001.