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. 2021 Mar 15;9:647702. doi: 10.3389/fcell.2021.647702

TABLE 1.

Correlation of YTHDF1 expression with clinicopathological parameters in GC patients (GSE29272).

Variables Cases (n) YTHDF1 expression
P
Low (%) High (%)
Age
≤60 75 52 (69.3) 23 (30.7) 0.1675
>60 51 41 (80.4) 10 (19.6)
Gender
Male 99 75 (75.8) 24 (24.2) 0.3428
Female 27 18 (66.7) 9 (33.3)
Tumor grade
1∼2 45 32 (71.1) 13 (28.9) 0.609
3 81 61 (75.3) 20 (24.7)
Pathological stage
I/II 10 10 (100.0) 0 (0.0) 0.0619
III/IV 116 83 (71.6) 33 (28.4)
Lymph node metastasis
No 26 21 (80.8) 5 (19.2) 0.333
Yes 98 70 (71.4) 28 (28.6)
Unknown 2 2 (100.0) 0 (0.0)
Family history of upper gastrointestinal cancer
No 97 69 (71.1) 28 (28.9) 0.2134
Yes 29 24 (82.8) 5 (17.2)
Lesion
GNCA 71 60 (84.5) 11 (15.5) 0.002**
GCA 55 33 (60.0) 22 (40.0)

**P < 0.01; GNCA, gastric non-cardia adenocarcinomas; GCA, gastric cardia adenocarcinomas.