Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 15;11:641261. doi: 10.3389/fcimb.2021.641261

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Geddes, Brustolini, Cavalcante, Moreira, de Castro, Guimarães, Gerber, Figueiredo, Diniz, Neto, Tanuri, Souza, Assunção-Miranda, Alves-Leon, Romão, de Souza, de Vasconcelos and de Aguiar

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

RT-qPCR validation of 16 selected DEGs co-modulated by CHIKV, MAYV, OROV, and ZIKV. hAST cells were infected with MOI 1 of CHIKV (A), MAYV (B), OROV (C) at 6 and 18 hpi and ZIKV (D) at 24 and 48 hpi and RT-qPCR was performed at indicated time points and compared to uninfected cells (n = 3 for each time point and condition). Data denotes p-values (y-axis) and mean fold change (x-axis) of infected cells relative to uninfected cells for 16 DEGs selected from commonly modulated genes in RNA-Seq dataset. Gene expression was normalized by endogenous HPRT1 levels. Red dots represent DEGs with at least 1 log2 Fold Change and P value ≤ 0.05. Blue dots represent DEGs with only P value ≤ 0.05. Green dots represent DEGs with at least 1 log2 Fold Change. Grey dots represent non-significant DEGs.