Fig. 42.
Pathway 40 Animal health: Potentially altered physiology in dsxFCRISPRh transgenic could lead it to vector animal disease not previously vectored by Anopheles gambiae. Relevant physiology would include immune system function or capacity for co-infection. These newly transmitted diseases would already be present in the environment into which the transgenics were released. The net effect of a population suppression gene drive would ultimately reduce the impact of this specific harm by reducing the density of mosquitoes, including transgenic ones. The components of vectorial capacity (V) that would be affected in this pathway are shown in red in the equation