Fig. 48.

Pathway 46 Animal health: Potential increases in livestock disease beyond pre-gene drive intervention levels following resurgence in pathogen transmission after initial population suppression would have reduced livestock immunity to pathogen. This could a potential harm for any successful vector control agent, not just population suppression gene drive, but is included for the sake of completeness. The analyses here are likely to lead to a ‘weight of evidence’ in favour or against the potential harm [42], rather than a definitive conclusion